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Welcome
to Zhao microfluidic Lab
We are seeking the key problems that were difficult to be handled with conventional approaches.
We are keen to develop new tools for biologists and demonstrate these new methods are very useful.
SELECTED PUBLICATIONS
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N. Li, W. Zhang, Z. Jin, Y. Huang, Z. Zhao, T. Chen, D. Wang, D. Zhang, M. Deng, C. Zheng, L. Zhao*, G. Guo, X. Wang*, A 3D Printed Meridian-Arrayed Microfluidic Device for Dual-Physical Fields Induced Highly Efficient Intracellular Delivery. Anal. Chem. 2025, 97, 15991-16003
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L. Zhao*, S. Xiong, D. Wang, X. Wang*, Microfluidic manipulation of the multicellular spheroids and organoids for modeling human diseases. Microchemical Journal 2025, 213, 113718.
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L. Zhao*, Z. Zhao, N. Li, X. Wang*, The nucleic acid detection using CRISPR/Cas biosensing system with micro-nano modality for point-of-care applications. Talanta 2025, 286, 127457.
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L. Zhao*#, L. Wang#, J. Huang, H. Chen, L. Liu, M. Shi, M. Zhang*, Label-Free Imaging of Mesenchymal Stem Cell Spheroid Differentiation with Flexible-Probe SECM and a Microfluidic Device. Anal. Chem. 2024, 96, 33, 13473–13481.
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L. Zhao, X. Wang*, 3D printed microfluidics for cell biological applications. TrAC Trends Anal. Chem. 2023, 158, 116864.
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M. Shi, L. Wang, Z. Xie, L. Zhao*, X. Zhang*, M. Zhang*, High-Content Label-Free Single-Cell Analysis with a Microfluidic Device Using Programmable Scanning Electrochemical Microscopy. (*corresponding) Anal. Chem. 2021, 93, 12417−12425.
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L. Zhao*#, Y. Liu#, Y. Liu#, M. Zhang, X. Zhang*, Microfluidic Control of Tumor and Stromal Cell Spheroids Pairing and Merging for Three-Dimensional Metastasis Study. (* corresponding, #equally contribution) Anal. Chem. 2020, 92, 11, 7638–7645.
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Z. Feng, D. Wang, Y. Zheng*, L. Zhao*, T. Xu, Z. Guo, M. I. Hussain, J. Zeng, L. Lou, Y. Sun, H. Jiang, A novel waterborne polyurethane with biodegradability and high flexibility for 3D printing. (*corresponding) Biofabrication, 2020, 12, 035015.
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Y. Liu, Y. Liu, X. Zheng, L. Zhao*, X. Zhang*, Recapitulating and Deciphering Tumor Microenvironment by Using 3D Printed Plastic Brick–Like Microfluidic Cell Patterning. (*corresponding) Adv. Healthcare Mater. 2020, 1901713.
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L. Zhao*#, J. Xiu#, Y. Liu, T. Zhang, W. Pan, X. Zheng, X. Zhang*, A 3D Printed Hanging Drop Dripper for Tumor Spheroids Analysis Without Recovery. (*Corresponding, #equally contribution) Sci. Rep. 9, 19717 (2019).
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J. Xiao, Y. Liu, L. Su*, D. Zhao, L. Zhao*, X. Zhang*, A Microfluidic Chip-based Wearable Colorimetric Sensor for Simple and Facile Detection of Sweat Glucose. (*Corresponding) Anal. Chem. 2019, 91, 23, 14803-14807.
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L. Zhao*#, M. Shi#, Y. Liu, X. Zheng, J. Xiu, Y. Liu, L. Tian, H. Wang, M. Zhang*, X. Zhang*, Systematic Analysis of Different Cell Spheroids with a Microfluidic Device Using Scanning Electrochemical Microscopy and Gene Expression Profiling. (*Corresponding, #equally contribution) Anal. Chem. 2019, 91, 7, 4307-4311.
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H. Qiao#, T. Guo#, Y. Zheng*, L. Zhao*, Y. Sun, Y. Liu, Y. Xie, A novel microporous oxidized bacterial cellulose/arginine composite and its effect on behavior of fibroblast/endothelial cell. (*Corresponding, #equally contribution) Carbohydr Polym. 2018, 184, 323-332.
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L. Zhao*#, T. Guo#, L. Wang, Y. Liu, G. Chen, H. Zhou, and M. Zhang*, Tape-Assisted Photolithographic-Free Microfluidic Chip Cell Patterning for Tumor Metastasis Study. (*-corresponding, #equally contribution) Anal. Chem. 2018, 90, 777–784.
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H. Zhou, L. Zhao*, X. Zhang*, In-Channel Printing-Device Opening Assay for Micropatterning Multiple Cells and Gene Analysis. (*-corresponding) Anal. Chem. 2015, 87, 2048−2053.
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Aaron M. Streets,# Xiannian Zhang,# Chen Cao, Yuhong Pang, Xinglong Wu, Liang Xiong, Lu Yang, Yusi Fu, Liang Zhao*, Fuchou Tang*, Yanyi Huang*, Microfluidic single-cell whole transcriptome sequencing. (* Corresponding, # equally contribution), Proc. Natl. Acad. Sci. USA 111, (19), 7048-7053 (2014) .
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C. Zheng#, L. Zhao#, G. Chen, Y. Zhou, Y. Pang, Y. Huang*, Quantitative study of the dynamic tumor-endothelial interactions through an integrated microfluidic coculture system. (#equally contribution), Anal. Chem., 2012, 84, 2088-2093.




